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By Paul H. Sugarbaker MD, FACS, FRCS (auth.), Santiago González-Moreno MD, PhD (eds.)

ISBN-10: 3540307591

ISBN-13: 9783540307594

ISBN-10: 3540307605

ISBN-13: 9783540307600

S. González-Moreno (Ed. ) Advances in Peritoneal floor Oncology With forty five Figures in fifty seven Separate Illustrations, 12 in colour and 19 Tables 123 IV Preface Santiago González-Moreno, MD, PhD division of Surgical Oncology Centro Oncológico MD Anderson overseas España Calle Gómez Hemans 2 28033 Madrid Spain sgonzalez@mdanderson. es Library of Congress keep watch over quantity: 2006937141 ISSN 0080-0015 ISBN 978-3-540-30759-4 Springer Berlin Heidelberg long island This paintings is topic to copyright. All rights are reserved, no matter if the complete or a part of the cloth is anxious, speci? ?cally the rights of translation, reprinting, reuse of illustrations, recitations, broadcasting, replica on micro? ?lm or in the other means, and garage in facts banks. Duplication of this ebook or components thereof is authorized purely lower than the provisions of the German Copyright legislations of September nine, 1965, in its present model, and permission to be used should always be acquired from Springer-Verlag. Violations are chargeable for prosecution below the German Copyright legislations. Springer is a part of Springer Science+Business Media http//www. springer. com Springer-Verlag Berlin Heidelberg 2007 revealed in Germany using normal descriptive names, logos, and so forth. during this ebook doesn't mean, even within the absence of a speci? ?c sta- ment, that such names are exempt from the proper protecting legislation and laws and for this reason unfastened for normal use. Product legal responsibility: The publishers can't warrantly the accuracy of any information regarding dosage and alertness contained during this booklet. In each case the consumer needs to payment such details by means of consulting the appropriate literature.

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Extra resources for Advances in Peritoneal Surface Oncology

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J Clin Pathol 48:849– 855 12. Douard R, Cugnenc P-H, Wind P, Benichou J (2004) Peritoneal involvement and free tumor cells in peritoneal cavity of patients with colon cancer. Am J Clin Pathol 121:154–155 13. Knudsen PJ (1991) The peritoneal elastic lamina. J Anat 177:41–46 14. Ludeman L, Shepherd NA (2005) Serosal involvement in gastrointestinal cancer: its assessment and significance. Histopathology 47:123–131 15. Moore GE, Sako K, Kondo T, Badillo J, Burke E (1961) Assessment of the exfoliation of tumour cells into the body cavities.

Not only is there controversy as to how to identify and classify serosal involvement in colonic cancer, there is also continuing debate concerning how common the phenomenon is and this will, of course, itself influence the prescient value of the parameter in the different major series. In our Gloucester, UK, series, only a very small proportion of cases (around 5%) represent Dukes stage A with cancer confined within the bowel wall and not fully penetrating the muscularis propia [6, 14]. On the other hand, LPI appears unusually common in the same series, with a rate of up to 57% [6, 7].

A comment is appropriate on the nature and likely site of serosal involvement in gastric cancer. Unsurprisingly, serosal involvement is more likely with diffuse tumours than with intestinal type, not least because the former are more likely to be associated with advanced stage [14]. Unlike with GI cancers at other sites, the stomach is the one organ where involvement of the peritoneum on a flat surface is more likely to be seen (Fig. 5). We believe that this is unlikely to reflect any differences in the micro-anatomy of the serosa of the stomach, compared to, say, the oesophagus and the colorectum, and it is more likely to be a manifestation of the biology of the tumour cells, with individual tumour cells, in the diffuse variety of gastric cancer, seemingly having more capability of transgressing the serosal surface and causing transcoelomic disease, and the fact that the stomach is liberally invested with a flat serosal surface.

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Advances in Peritoneal Surface Oncology by Paul H. Sugarbaker MD, FACS, FRCS (auth.), Santiago González-Moreno MD, PhD (eds.)


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