By Silvio Garattini
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Extra resources for Advances in Pharmacology and Chemotherapy Volume 13
London. , Kadison, E. , Shalaes, W. , and Felsenfeld, 0. (1953). Antibiot. Chernother. ) 3, 151-157. Moon, A. , and Coleman, J. F. (1962). Bol. Chil. Parasitol. 17, 63-66. Moraes, G. E. , Faria, J. , and Fernandes, J. F. (1960). Rev. Inst. Med. Trop. Sao Paul0 2, 147-154. Neal, R. A. (1973). Proc. Znt. Cong. Trop. Med. Malaria 9th 1, 56. Neal, R. , and Miles, R. A. (1970). Rev. Znst. Med. Trop. Sao Paulo 12, 325-332. Neal, R. , Richards, W. H. , and Fareobrother, D. A. (1973). Trans. Roy. Soc. Trop.
225, 210-236. Fulton, J. D. (1943). Ann. Trop. Med. Parasitol. 37, 164-173. Fulton, J. , and Spooner, D. F. (1959). Exp. Parasitol. 8, 137-162. Ghosh, B. , and Chatterjee, A. N. (1961). Ann. Biochem. Exp. Med. 21, 343-354. Ghosh, B. K . , and Chatterjee, A. N. (1962). Antibiot. and Chemother. (Washington, D . C . ) 12,204-208. Goble, F. C. (1949). J . Parasitol. 35,375-378. Goble, F. C. (1950). J . Pharmacol. E x p . Ther. 98, 49-61. Goble, F. C. (1951). J. Parasitol. 37,408-414. Goble, F. C. (1952a).
The patients with prolonged negative serology were therefore considered cured. Such remarkable results with nitrofuran compounds have not, however, been entirely confirmed in Brazil by Rassi and Ferreira (1971), who treated a small group of 13 patients in the acute phase with Nifurtimox, according to the same schedule. 5%, respectively, of the patients. 1%). D. TREATMENT IN THE CHRONIC PHASE Contrary to what occurs in the acute phase, serological reactions are not affected by treatment with nitrofuran derivatives.
Advances in Pharmacology and Chemotherapy Volume 13 by Silvio Garattini